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Loss of CENP-I Impairs Homologous Recombination and Sensitizes Cells to PARP1 Inhibition
SIMPLE SUMMARY: Centromere Protein I (CENP-I) is one of a family of cellular molecules that is essential for the separation of chromosomes during mitosis and mitotic progression. Interestingly, other CENP family proteins, such as CENP-A, have been shown to be involved in double-strand break repair....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267748/ https://www.ncbi.nlm.nih.gov/pubmed/34206916 http://dx.doi.org/10.3390/cancers13133202 |