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Loss of CENP-I Impairs Homologous Recombination and Sensitizes Cells to PARP1 Inhibition

SIMPLE SUMMARY: Centromere Protein I (CENP-I) is one of a family of cellular molecules that is essential for the separation of chromosomes during mitosis and mitotic progression. Interestingly, other CENP family proteins, such as CENP-A, have been shown to be involved in double-strand break repair....

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Detalles Bibliográficos
Autores principales: Dang, Tuyen T., Morales, Julio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267748/
https://www.ncbi.nlm.nih.gov/pubmed/34206916
http://dx.doi.org/10.3390/cancers13133202