Inhibition of miR-222 by Oncolytic Adenovirus-Encoded miRNA Sponges Promotes Viral Oncolysis and Elicits Antitumor Effects in Pancreatic Cancer Models

SIMPLE SUMMARY: Oncolytic adenoviruses are replication-competent viruses engineered for use in cancer treatment. However, the transformation of cancer cells defines a scenario in which the viruses are not adapted to replicate. During tumorigenesis, a large number of miRNAs are deregulated, modulatin...

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Detalles Bibliográficos
Autores principales: Raimondi, Giulia, Gea-Sorlí, Sabrina, Otero-Mateo, Marc, Fillat, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267801/
https://www.ncbi.nlm.nih.gov/pubmed/34203557
http://dx.doi.org/10.3390/cancers13133233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267801/
https://www.ncbi.nlm.nih.gov/pubmed/34203557
http://dx.doi.org/10.3390/cancers13133233

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