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Investigation of the Detailed AMPylated Reaction Mechanism for the Huntingtin Yeast-Interacting Protein E Enzyme HYPE

AMPylation is a prevalent posttranslational modification that involves the addition of adenosine monophosphate (AMP) to proteins. Exactly how Huntingtin-associated yeast-interacting protein E (HYPE), as the first human protein, is involved in the transformation of the AMP moiety to its substrate tar...

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Detalles Bibliográficos
Autores principales: Liu, Meili, Huai, Zhe, Tan, Hongwei, Chen, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267892/
https://www.ncbi.nlm.nih.gov/pubmed/34209803
http://dx.doi.org/10.3390/ijms22136999

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