Exosomal miR-183-5p Shuttled by M2 Polarized Tumor-Associated Macrophage Promotes the Development of Colon Cancer via Targeting THEM4 Mediated PI3K/AKT and NF-κB Pathways

BACKGROUND: Abnormal accumulation of macrophages in the colon cancer (CC) contribute to its progression. miR-183-5p has been confirmed as an oncogene in CC and this article explores the effect and mechanism of exosomal miR-183-5p enriched by M2-polarized tumor-associated macrophages (TAM) on CC cell...

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Detalles Bibliográficos
Autores principales: Zhang, Shangxin, Li, Deguan, Zhao, Min, Yang, Fei, Sang, Changye, Yan, Changhong, Wang, Zhenjun, Li, Yongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267908/
https://www.ncbi.nlm.nih.gov/pubmed/34249713
http://dx.doi.org/10.3389/fonc.2021.672684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267908/
https://www.ncbi.nlm.nih.gov/pubmed/34249713
http://dx.doi.org/10.3389/fonc.2021.672684

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