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Conversion of Anergic T Cells Into Foxp3(-) IL-10(+) Regulatory T Cells by a Second Antigen Stimulus In Vivo

T cell anergy is a common mechanism of T cell tolerance. However, although anergic T cells are retained for longer time periods in their hosts, they remain functionally passive. Here, we describe the induction of anergic CD4(+) T cells in vivo by intravenous application of high doses of antigen and...

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Detalles Bibliográficos
Autores principales: Thomann, Anna Sophie, Schneider, Theresa, Cyran, Laura, Eckert, Ina Nathalie, Kerstan, Andreas, Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267912/
https://www.ncbi.nlm.nih.gov/pubmed/34249012
http://dx.doi.org/10.3389/fimmu.2021.704578