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Conversion of Anergic T Cells Into Foxp3(-) IL-10(+) Regulatory T Cells by a Second Antigen Stimulus In Vivo
T cell anergy is a common mechanism of T cell tolerance. However, although anergic T cells are retained for longer time periods in their hosts, they remain functionally passive. Here, we describe the induction of anergic CD4(+) T cells in vivo by intravenous application of high doses of antigen and...
Autores principales: | Thomann, Anna Sophie, Schneider, Theresa, Cyran, Laura, Eckert, Ina Nathalie, Kerstan, Andreas, Lutz, Manfred B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267912/ https://www.ncbi.nlm.nih.gov/pubmed/34249012 http://dx.doi.org/10.3389/fimmu.2021.704578 |
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