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ADAM9-Responsive Mesoporous Silica Nanoparticles for Targeted Drug Delivery in Pancreatic Cancer

SIMPLE SUMMARY: The clinical efficacy of systemic chemotherapy is limited in pancreatic cancer (PDAC) due to toxicity-dependent dose-limitations often leading to premature cessation of therapy. Targeted delivery of chemotherapeutic drugs to cancer cells, without affecting healthy nontumor cells, wil...

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Detalles Bibliográficos
Autores principales: Slapak, Etienne J., Kong, Lily, el Mandili, Mouad, Nieuwland, Rienk, Kros, Alexander, Bijlsma, Maarten F., Spek, C. Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268056/
https://www.ncbi.nlm.nih.gov/pubmed/34282781
http://dx.doi.org/10.3390/cancers13133321