Differential Effects of Halofuginone Enantiomers on Muscle Fibrosis and Histopathology in Duchenne Muscular Dystrophy

Progressive loss of muscle and muscle function is associated with significant fibrosis in Duchenne muscular dystrophy (DMD) patients. Halofuginone, an analog of febrifugine, prevents fibrosis in various animal models, including those of muscular dystrophies. Effects of (+)/(−)-halofuginone enantiome...

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Detalles Bibliográficos
Autores principales: Mordechay, Sharon, Smullen, Shaun, Evans, Paul, Genin, Olga, Pines, Mark, Halevy, Orna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268105/
https://www.ncbi.nlm.nih.gov/pubmed/34209117
http://dx.doi.org/10.3390/ijms22137063

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