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Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma
SIMPLE SUMMARY: ctDNA assay is a promising non-invasive method to detect genomic alterations associated with lung cancer. In this prospective study of 25 patients with EGFR-mutant lung adenocarcinoma receiving osimertinib, ctDNA progression predated radiographic progression by 118 days in 11 of 20 p...
Autores principales: | Kim, Chul, Xi, Liqiang, Cultraro, Constance M., Wei, Fang, Jones, Gregory, Cheng, Jordan, Shafiei, Ahmad, Pham, Trinh Hoc-Tran, Roper, Nitin, Akoth, Elizabeth, Ghafoor, Azam, Misra, Vikram, Monkash, Nina, Strom, Charles, Tu, Michael, Liao, Wei, Chia, David, Morris, Clive, Steinberg, Seth M., Bagheri, Hadi, Wong, David T. W., Raffeld, Mark, Guha, Udayan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268167/ https://www.ncbi.nlm.nih.gov/pubmed/34283064 http://dx.doi.org/10.3390/cancers13133342 |
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