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CD33 Expression and Gentuzumab Ozogamicin in Acute Myeloid Leukemia: Two Sides of the Same Coin
SIMPLE SUMMARY: Roughly 85–90% of adult and pediatric acute myeloid leukemia (AML) are CD33-positive. Gemtuzumab ozogamicin (GO), a humanized murine IgG4 anti-CD33 antibody, is the first target therapy approved in AML therapeutic scenario. This review focuses on current biological information and cl...
Autores principales: | Molica, Matteo, Perrone, Salvatore, Mazzone, Carla, Niscola, Pasquale, Cesini, Laura, Abruzzese, Elisabetta, de Fabritiis, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268215/ https://www.ncbi.nlm.nih.gov/pubmed/34203180 http://dx.doi.org/10.3390/cancers13133214 |
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