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ADCC-Inducing Antibody Trastuzumab and Selection of KIR-HLA Ligand Mismatched Donors Enhance the NK Cell Anti-Breast Cancer Response

SIMPLE SUMMARY: Natural killer (NK) cells are potent killers of tumor cells. Many tumors, including breast cancers, develop mechanisms to suppress anti-tumor immune responses, requiring the development of strategies to overcome suppression. Here, we tested a combination therapy that aims to (1) enha...

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Detalles Bibliográficos
Autores principales:	Ehlers, Femke A. I., Beelen, Nicky A., van Gelder, Michel, Evers, Tom M. J., Smidt, Marjolein L., Kooreman, Loes F. S., Bos, Gerard M. J., Wieten, Lotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268223/ https://www.ncbi.nlm.nih.gov/pubmed/34203549 http://dx.doi.org/10.3390/cancers13133232

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