Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M(pro) and Its Antiviral Activity in Cells against SARS-CoV-2

The development of new antiviral drugs against SARS-CoV-2 is a valuable long-term strategy to protect the global population from the COVID-19 pandemic complementary to the vaccination. Considering this, the viral main protease (M(pro)) is among the most promising molecular targets in light of its im...

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Detalles Bibliográficos
Autores principales: Mangiavacchi, Francesca, Botwina, Pawel, Menichetti, Elena, Bagnoli, Luana, Rosati, Ornelio, Marini, Francesca, Fonseca, Sérgio F., Abenante, Laura, Alves, Diego, Dabrowska, Agnieszka, Kula-Pacurar, Anna, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Rizzuti, Bruno, Abian, Olga, Lenardão, Eder J., Velazquez-Campoy, Adrian, Pyrc, Krzysztof, Sancineto, Luca, Santi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268238/
https://www.ncbi.nlm.nih.gov/pubmed/34208928
http://dx.doi.org/10.3390/ijms22137048

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