Cargando…

LINC00115 promotes stemness and inhibits apoptosis of ovarian cancer stem cells by upregulating SOX9 and inhibiting the Wnt/β-catenin pathway through competitively binding to microRNA-30a

OBJECTIVE: Long non-coding RNAs (lncRNAs) and microRNAs (miRs) are differentially expressed in ovarian cancer (OC) cells and influence OC progression. This study intended to explore the underlying roles of LINC00115 and miR-30a in OC. METHODS: Gene Expression Omnibus database was used to find OC mic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Rui, Jiang, Luo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268259/ https://www.ncbi.nlm.nih.gov/pubmed/34238293 http://dx.doi.org/10.1186/s12935-021-02019-2

Ejemplares similares

Downregulation of LINC00115 inhibits the proliferation and invasion of lung cancer cells in vitro and in vitro
por: Shao, Lili, et al.
Publicado: (2021)

Long noncoding RNA LINC00115 promotes breast cancer metastasis by inhibiting miR‐7
por: Yuan, Chunlei, et al.
Publicado: (2020)

Down‐regulated LINC00115 inhibits prostate cancer cell proliferation and invasion via targeting miR‐212‐5p/FZD5/Wnt/β‐catenin axis
por: Peng, Naixiong, et al.
Publicado: (2021)

Up-regulation of microRNA-200c-3p inhibits invasion and migration of renal cell carcinoma cells via the SOX2-dependent Wnt/β-catenin signaling pathway
por: Li, Shuai, et al.
Publicado: (2019)

Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition
por: Wang, Jing, et al.
Publicado: (2015)

LINC00662 enhances cell progression and stemness in breast cancer by MiR-144-3p/SOX2 axis
por: An, Congjing, et al.
Publicado: (2022)

Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer
por: Wei, Jinlai, et al.
Publicado: (2022)

Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the β-catenin pathway
por: Zhou, Yongping, et al.
Publicado: (2020)

MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway
por: Zheng, Zhiyun, et al.
Publicado: (2016)

TRIP6 enhances stemness property of breast cancer cells through activation of Wnt/β-catenin
por: Zhao, Xiaohui, et al.
Publicado: (2020)

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
por: Liu, Qian-Qian, et al.
Publicado: (2016)

TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma
por: Tong, Qing, et al.
Publicado: (2022)

MiR-924 as a tumor suppressor inhibits non-small cell lung cancer by inhibiting RHBDD1/Wnt/β-catenin signaling pathway
por: Wang, Huaishi, et al.
Publicado: (2020)

TACR2 is associated with the immune microenvironment and inhibits migration and proliferation via the Wnt/β-catenin signaling pathway in prostate cancer
por: Jianfeng, Wang, et al.
Publicado: (2021)

LINC00908 negatively regulates microRNA-483-5p to increase TSPYL5 expression and inhibit the development of prostate cancer
por: Fan, Li, et al.
Publicado: (2020)

Knockdown of AGGF1 inhibits the invasion and migration of gastric cancer via epithelial–mesenchymal transition through Wnt/β-catenin pathway
por: Yao, Han-Hui, et al.
Publicado: (2019)

β-Catenin/LEF-1 transcription complex is responsible for the transcriptional activation of LINC01278
por: Lin, Shaojian, et al.
Publicado: (2021)

Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness
por: Schmidtova, Silvia, et al.
Publicado: (2020)

Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/β-catenin signaling pathway by down-regulating KLK4
por: Tang, Lin, et al.
Publicado: (2019)

PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway
por: Zhang, Wei, et al.
Publicado: (2021)

SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer
por: Han, Fei, et al.
Publicado: (2018)

Silencing LGR6 Attenuates Stemness and Chemoresistance via Inhibiting Wnt/β-Catenin Signaling in Ovarian Cancer
por: Ruan, Xiaohong, et al.
Publicado: (2019)

Overexpression of microRNA-367 inhibits angiogenesis in ovarian cancer by downregulating the expression of LPA1
por: Zheng, Qingling, et al.
Publicado: (2020)

MicroRNA-214-3p inhibits the stem-like properties of lung squamous cell cancer by targeting YAP1
por: Lu, Tingting, et al.
Publicado: (2020)

circ_0061265 competitively binds to microRNA-885-3p to promote the development of gastric cancer by upregulating AURKA expression
por: Fei, Qian, et al.
Publicado: (2022)

Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24(+)CD44(+) pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway
por: Zhou, Jingyang, et al.
Publicado: (2020)

Downregulation of Tim-1 inhibits the proliferation, migration and invasion of glioblastoma cells via the miR-133a/TGFBR1 axis and the restriction of Wnt/β-catenin pathway
por: Wei, Li, et al.
Publicado: (2021)

Inhibition of cancer cell-derived exosomal microRNA-183 suppresses cell growth and metastasis in prostate cancer by upregulating TPM1
por: Dai, Yanping, et al.
Publicado: (2021)

STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/β-Catenin Signaling
por: Xie, Min, et al.
Publicado: (2021)

Neuropilin-1 is upregulated by Wnt/β-catenin signaling and is important for mammary stem cells
por: Liu, Wei, et al.
Publicado: (2017)

PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway
por: Luo, Jing, et al.
Publicado: (2019)

PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β-catenin signaling pathway
por: Ma, Dede, et al.
Publicado: (2020)

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway
por: Liu, Tong, et al.
Publicado: (2015)

LNC00115 Mediates Cisplatin Resistance by Regulating the miR-7/ERK Signalling Pathway in Ovarian Cancer
por: Jiang, Xinyan, et al.
Publicado: (2021)

R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells
por: Liu, Si, et al.
Publicado: (2018)

LINC00689 promotes prostate cancer progression via regulating miR-496/CTNNB1 to activate Wnt pathway
por: Meng, Liwei, et al.
Publicado: (2020)

CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells
por: Chang, Guoqiang, et al.
Publicado: (2013)

FOXH1 promotes lung cancer progression by activating the Wnt/β-catenin signaling pathway
por: Zhang, Jun, et al.
Publicado: (2021)

Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway
por: Chai, Dahai, et al.
Publicado: (2023)

Role of microRNA-92a in metastasis of osteosarcoma cells in vivo and in vitro by inhibiting expression of TCF21 with the transmission of bone marrow derived mesenchymal stem cells
por: Cao, Shuai, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d9p93pm0shevbdg8ibo61talnf