Nuclear Export Inhibitor KPT-8602 Synergizes with PARP Inhibitors in Escalating Apoptosis in Castration Resistant Cancer Cells

Aberrant nuclear protein transport, often observed in cancer, causes mislocalization-dependent inactivation of critical cellular proteins. Earlier we showed that overexpression of exportin 1 is linked to higher grade and Gleason score in metastatic castration resistant prostate cancer (mCRPC). We al...

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Detalles Bibliográficos
Autores principales: Uddin, Md. Hafiz, Li, Yiwei, Khan, Husain Yar, Muqbil, Irfana, Aboukameel, Amro, Sexton, Rachel E., Reddy, Shriya, Landesman, Yosef, Kashyap, Trinayan, Azmi, Asfar S., Heath, Elisabeth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268282/
https://www.ncbi.nlm.nih.gov/pubmed/34206543
http://dx.doi.org/10.3390/ijms22136676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268282/
https://www.ncbi.nlm.nih.gov/pubmed/34206543
http://dx.doi.org/10.3390/ijms22136676

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