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The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota

BACKGROUND: Autism spectrum disorders (ASD) are associated with dysregulation of the microbiota-gut-brain axis, changes in microbiota composition as well as in the fecal, serum, and urine levels of microbial metabolites. Yet a causal relationship between dysregulation of the microbiota-gut-brain axi...

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Detalles Bibliográficos
Autores principales: Bermudez-Martin, Patricia, Becker, Jérôme A. J., Caramello, Nicolas, Fernandez, Sebastian P., Costa-Campos, Renan, Canaguier, Juliette, Barbosa, Susana, Martinez-Gili, Laura, Myridakis, Antonis, Dumas, Marc-Emmanuel, Bruneau, Aurélia, Cherbuy, Claire, Langella, Philippe, Callebert, Jacques, Launay, Jean-Marie, Chabry, Joëlle, Barik, Jacques, Le Merrer, Julie, Glaichenhaus, Nicolas, Davidovic, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268286/
https://www.ncbi.nlm.nih.gov/pubmed/34238386
http://dx.doi.org/10.1186/s40168-021-01103-z