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Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock

PURPOSE: Severe cardiogenic shock is the major driver of mortality on cardiologic intensive care units. Novel therapeutic options like extracorporeal membrane oxygenation (ECMO) or the combination of ECMO and a percutaneous microaxial pump like Impella CP (ECMELLA) are promising Options. Here we wan...

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Autores principales: Lüsebrink, Enzo, Massberg, Steffen, Orban, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268316/
https://www.ncbi.nlm.nih.gov/pubmed/34263084
http://dx.doi.org/10.1002/hsr2.321
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author Lüsebrink, Enzo
Massberg, Steffen
Orban, Martin
author_facet Lüsebrink, Enzo
Massberg, Steffen
Orban, Martin
author_sort Lüsebrink, Enzo
collection PubMed
description PURPOSE: Severe cardiogenic shock is the major driver of mortality on cardiologic intensive care units. Novel therapeutic options like extracorporeal membrane oxygenation (ECMO) or the combination of ECMO and a percutaneous microaxial pump like Impella CP (ECMELLA) are promising Options. Here we want to focus on the question what happens when left ventricular preload is too low to unload in cardiogenic shock in patients with ECMELLA and this aspect is illustrated by transesophageal echocardiography. METHODS: We detail a case of a 43‐year‐old active smoker who was admitted for acute myocardial infarction causing severe cardiogenic shock and who was finally treated with ECMELLA. Transesophageal echocardiography is used to illustrate what happens when left ventricle (LV) preload is too low to unload. RESULTS: Transesophageal echocardiography demonstrates complete collapse of LV and LA as consequence of increased but still low flow rate of the coaxial pump. CONCLUSION: Novel therapeutic options like ECMO and percutaneous microaxial pumps like Impella CP, 5.0 or the combination of both (ECMELLA), are promising options. Whether these approaches reduce mortality has to be evaluated in urgently needed randomized trials but results will not be available in the next few years.
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spelling pubmed-82683162021-07-13 Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock Lüsebrink, Enzo Massberg, Steffen Orban, Martin Health Sci Rep Clinical Image PURPOSE: Severe cardiogenic shock is the major driver of mortality on cardiologic intensive care units. Novel therapeutic options like extracorporeal membrane oxygenation (ECMO) or the combination of ECMO and a percutaneous microaxial pump like Impella CP (ECMELLA) are promising Options. Here we want to focus on the question what happens when left ventricular preload is too low to unload in cardiogenic shock in patients with ECMELLA and this aspect is illustrated by transesophageal echocardiography. METHODS: We detail a case of a 43‐year‐old active smoker who was admitted for acute myocardial infarction causing severe cardiogenic shock and who was finally treated with ECMELLA. Transesophageal echocardiography is used to illustrate what happens when left ventricle (LV) preload is too low to unload. RESULTS: Transesophageal echocardiography demonstrates complete collapse of LV and LA as consequence of increased but still low flow rate of the coaxial pump. CONCLUSION: Novel therapeutic options like ECMO and percutaneous microaxial pumps like Impella CP, 5.0 or the combination of both (ECMELLA), are promising options. Whether these approaches reduce mortality has to be evaluated in urgently needed randomized trials but results will not be available in the next few years. John Wiley and Sons Inc. 2021-07-09 /pmc/articles/PMC8268316/ /pubmed/34263084 http://dx.doi.org/10.1002/hsr2.321 Text en © 2021 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Image
Lüsebrink, Enzo
Massberg, Steffen
Orban, Martin
Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
title Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
title_full Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
title_fullStr Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
title_full_unstemmed Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
title_short Combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
title_sort combined extracorporeal membrane oxygenation and microaxial pump—when left ventricular preload is too low to unload in cardiogenic shock
topic Clinical Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268316/
https://www.ncbi.nlm.nih.gov/pubmed/34263084
http://dx.doi.org/10.1002/hsr2.321
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