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Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study

Diabetes mellitus (DM) is one of the leading causes of chronic kidney disease (CKD). We analyzed the prevalence of CKD in the population with diabetes in Extremadura (Spain). retrospective observational study was carried in the diabetic population attended in the Extremadura Health System in 2012–20...

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Autores principales: Fernández-Fernández, Leandro, Barquilla-García, Alfonso, Sánchez-Vega, Javier, Risco-Solanilla, José Carlos, Suárez-González, Félix, Buitrago, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268326/
https://www.ncbi.nlm.nih.gov/pubmed/34209644
http://dx.doi.org/10.3390/jcm10132886
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author Fernández-Fernández, Leandro
Barquilla-García, Alfonso
Sánchez-Vega, Javier
Risco-Solanilla, José Carlos
Suárez-González, Félix
Buitrago, Francisco
author_facet Fernández-Fernández, Leandro
Barquilla-García, Alfonso
Sánchez-Vega, Javier
Risco-Solanilla, José Carlos
Suárez-González, Félix
Buitrago, Francisco
author_sort Fernández-Fernández, Leandro
collection PubMed
description Diabetes mellitus (DM) is one of the leading causes of chronic kidney disease (CKD). We analyzed the prevalence of CKD in the population with diabetes in Extremadura (Spain). retrospective observational study was carried in the diabetic population attended in the Extremadura Health System in 2012–2014. A total of 38,253 patients, ≥18 years old were included. Estimated glomerular filtration rate (eGFR) was calculated using the CKD Epidemiology Collaboration equation. CKD was defined as follow: an eGFR <60 mL/min/1.73 m(2) in a time period ≥ of three months or the presence of renal damage, with or without reduced eGFR, if the urine albumin-creatinine ratio (UACR) was ≥30 mg/g, also in a time period ≥ of three months. The prevalence rate of CKD was 25.3% (27.6% in women; 23.0% in men) and increases with age (34.0% in ≥65 years-olds). 24.9% of patients with CKD were in the very-high risk category for cardiovascular events (6.3% of the diabetic population). If CKD were diagnosed without requiring sustained eGFR <60 mL/min/1.73 m(2) and/or sustained UACR ≥30 mg/g (as it is frequently found in the literature) this would overestimate the prevalence of CKD by 23%.
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spelling pubmed-82683262021-07-10 Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study Fernández-Fernández, Leandro Barquilla-García, Alfonso Sánchez-Vega, Javier Risco-Solanilla, José Carlos Suárez-González, Félix Buitrago, Francisco J Clin Med Article Diabetes mellitus (DM) is one of the leading causes of chronic kidney disease (CKD). We analyzed the prevalence of CKD in the population with diabetes in Extremadura (Spain). retrospective observational study was carried in the diabetic population attended in the Extremadura Health System in 2012–2014. A total of 38,253 patients, ≥18 years old were included. Estimated glomerular filtration rate (eGFR) was calculated using the CKD Epidemiology Collaboration equation. CKD was defined as follow: an eGFR <60 mL/min/1.73 m(2) in a time period ≥ of three months or the presence of renal damage, with or without reduced eGFR, if the urine albumin-creatinine ratio (UACR) was ≥30 mg/g, also in a time period ≥ of three months. The prevalence rate of CKD was 25.3% (27.6% in women; 23.0% in men) and increases with age (34.0% in ≥65 years-olds). 24.9% of patients with CKD were in the very-high risk category for cardiovascular events (6.3% of the diabetic population). If CKD were diagnosed without requiring sustained eGFR <60 mL/min/1.73 m(2) and/or sustained UACR ≥30 mg/g (as it is frequently found in the literature) this would overestimate the prevalence of CKD by 23%. MDPI 2021-06-29 /pmc/articles/PMC8268326/ /pubmed/34209644 http://dx.doi.org/10.3390/jcm10132886 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fernández-Fernández, Leandro
Barquilla-García, Alfonso
Sánchez-Vega, Javier
Risco-Solanilla, José Carlos
Suárez-González, Félix
Buitrago, Francisco
Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study
title Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study
title_full Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study
title_fullStr Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study
title_full_unstemmed Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study
title_short Prevalence of Chronic Kidney Disease in Patients with Diabetes in Extremadura (Spain) during the Years 2012, 2013 and 2014: An Observational Study
title_sort prevalence of chronic kidney disease in patients with diabetes in extremadura (spain) during the years 2012, 2013 and 2014: an observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268326/
https://www.ncbi.nlm.nih.gov/pubmed/34209644
http://dx.doi.org/10.3390/jcm10132886
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