The Janus Face of IL-33 Signaling in Tumor Development and Immune Escape

SIMPLE SUMMARY: Interleukin-33 (IL-33) is often released from damaged cells, acting as a danger signal. IL-33 exerts its function by interacting with its receptor suppression of tumorigenicity 2 (ST2) that is constitutively expressed on most immune cells. Therefore, IL-33/ST2 signaling can modulate...

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Detalles Bibliográficos
Autores principales: Choi, Mi-Ran, Sosman, Jeffrey A., Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268428/
https://www.ncbi.nlm.nih.gov/pubmed/34209038
http://dx.doi.org/10.3390/cancers13133281

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