Cargando…
CYLD Inhibits the Development of Skin Squamous Cell Tumors in Immunocompetent Mice
Cylindromatosis (CYLD) is a deubiquitinase (DUB) enzyme that was initially characterized as a tumor suppressor of adnexal skin tumors in patients with CYLD syndrome. Later, it was also shown that the expression of functionally inactive mutated forms of CYLD promoted tumor development and progression...
Autores principales: | Alameda, Josefa P., García-García, Verónica A., López, Silvia, Hernando, Ana, Page, Angustias, Navarro, Manuel, Moreno-Maldonado, Rodolfo, Paramio, Jesús M., Ramírez, Ángel, García-Fernández, Rosa A., Casanova, María Llanos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268443/ https://www.ncbi.nlm.nih.gov/pubmed/34201751 http://dx.doi.org/10.3390/ijms22136736 |
Ejemplares similares
-
Premature aging and cancer development in transgenic mice lacking functional CYLD
por: Alameda, Josefa P., et al.
Publicado: (2019) -
Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53
por: Page, Angustias, et al.
Publicado: (2016) -
Correction: Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53
por: Page, Angustias, et al.
Publicado: (2017) -
IKKα Induces Epithelial–Mesenchymal Changes in Mouse Skin Carcinoma Cells That Can Be Partially Reversed by Apigenin
por: García-García, Verónica A., et al.
Publicado: (2022) -
Increased IKKα Expression in the Basal Layer of the Epidermis of Transgenic Mice Enhances the Malignant Potential of Skin Tumors
por: Alameda, Josefa P., et al.
Publicado: (2011)