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Less Carcinogenic Chlorinated Estrogens Applicable to Hormone Replacement Therapy
Human estrogens prescribed for hormone replacement therapy (HRT) are known to be potent carcinogens. To find safer estrogens, several chlorinated estrogens were synthesized and their carcinogenic potential were determined. A pellet containing either 2-chloro-17β-estradiol (2-ClE(2)) or 4-chloro-17β-...
Autores principales: | Okamoto, Yoshinori, Jinno, Hideto, Itoh, Shinji, Shibutani, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268473/ https://www.ncbi.nlm.nih.gov/pubmed/34281275 http://dx.doi.org/10.3390/ijms22137222 |
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