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Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?

Pulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because...

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Autores principales: Farmakis, Ioannis T., Demerouti, Eftychia, Karyofyllis, Panagiotis, Karatasakis, George, Stratinaki, Maria, Tsiapras, Dimitrios, Athanassopoulos, George, Voudris, Vassilios, Giannakoulas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268493/
https://www.ncbi.nlm.nih.gov/pubmed/34206876
http://dx.doi.org/10.3390/jcm10132826
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author Farmakis, Ioannis T.
Demerouti, Eftychia
Karyofyllis, Panagiotis
Karatasakis, George
Stratinaki, Maria
Tsiapras, Dimitrios
Athanassopoulos, George
Voudris, Vassilios
Giannakoulas, George
author_facet Farmakis, Ioannis T.
Demerouti, Eftychia
Karyofyllis, Panagiotis
Karatasakis, George
Stratinaki, Maria
Tsiapras, Dimitrios
Athanassopoulos, George
Voudris, Vassilios
Giannakoulas, George
author_sort Farmakis, Ioannis T.
collection PubMed
description Pulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because right heart failure is the predominant cause of death in PAH patients. Given its wide availability and reduced cost, echocardiography is of paramount importance in the evaluation of the right heart in PAH. Several echocardiographic parameters have been shown to have prognostic implications in PAH; however, the role of echocardiography in the risk assessment of the PAH patient is limited under the current guidelines. This review discusses the echocardiographic evaluation of the RV in PAH and during therapy, and its prognostic implications, as well as the potential significant role of repeated echocardiographic assessment in the follow-up of patients with PAH.
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spelling pubmed-82684932021-07-10 Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility? Farmakis, Ioannis T. Demerouti, Eftychia Karyofyllis, Panagiotis Karatasakis, George Stratinaki, Maria Tsiapras, Dimitrios Athanassopoulos, George Voudris, Vassilios Giannakoulas, George J Clin Med Review Pulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because right heart failure is the predominant cause of death in PAH patients. Given its wide availability and reduced cost, echocardiography is of paramount importance in the evaluation of the right heart in PAH. Several echocardiographic parameters have been shown to have prognostic implications in PAH; however, the role of echocardiography in the risk assessment of the PAH patient is limited under the current guidelines. This review discusses the echocardiographic evaluation of the RV in PAH and during therapy, and its prognostic implications, as well as the potential significant role of repeated echocardiographic assessment in the follow-up of patients with PAH. MDPI 2021-06-26 /pmc/articles/PMC8268493/ /pubmed/34206876 http://dx.doi.org/10.3390/jcm10132826 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Farmakis, Ioannis T.
Demerouti, Eftychia
Karyofyllis, Panagiotis
Karatasakis, George
Stratinaki, Maria
Tsiapras, Dimitrios
Athanassopoulos, George
Voudris, Vassilios
Giannakoulas, George
Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_full Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_fullStr Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_full_unstemmed Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_short Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_sort echocardiography in pulmonary arterial hypertension: is it time to reconsider its prognostic utility?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268493/
https://www.ncbi.nlm.nih.gov/pubmed/34206876
http://dx.doi.org/10.3390/jcm10132826
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