Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer

SIMPLE SUMMARY: Bowel cancer is a serious disease, which affects many people worldwide. Unfortunately, the disease is often diagnosed in an advanced stage, which impairs the chance of survival. Furthermore, resistance to therapy occurs frequently. Thus, novel therapeutic approaches are required to i...

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Detalles Bibliográficos
Autores principales: Jiso, Apisada, Demuth, Philipp, Bachowsky, Madeleine, Haas, Manuel, Seiwert, Nina, Heylmann, Daniel, Rasenberger, Birgit, Christmann, Markus, Dietrich, Lea, Brunner, Thomas, Riyanti, Schäberle, Till F., Plubrukarn, Anuchit, Fahrer, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268692/
https://www.ncbi.nlm.nih.gov/pubmed/34209047
http://dx.doi.org/10.3390/cancers13133282

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