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High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

SIMPLE SUMMARY: We retrospectively analyzed 304 patients with surgically removed non-small cell lung cancer (NSCLC). Multiplex antibody staining of nuclear factor erythroid 2-related factor 2 (NRF2) and thioredoxin reductase 1 (TrxR1) was conducted and scored in cytokeratin-positive (CK+) cells with...

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Detalles Bibliográficos
Autores principales:	Tsakonas, Georgios, Martín-Bernabé, Alfonso, Rounis, Konstantinos, Moreno-Ruiz, Pablo, Botling, Johan, De Petris, Luigi, Ylipää, Antti, Mezheyeuski, Artur, Micke, Patrick, Östman, Arne, Ekman, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268817/ https://www.ncbi.nlm.nih.gov/pubmed/34202448 http://dx.doi.org/10.3390/cancers13133151

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