Germline ERBB2/HER2 Coding Variants Are Associated with Increased Risk of Myeloproliferative Neoplasms

SIMPLE SUMMARY: Familial clustering of myeloproliferative neoplasms (MPN) is well known, with a 5- to 7-fold increased risk of MPN among first-degree relatives of MPN patients. However, the genetic susceptibility of this disease remains poorly understood. Exome sequencing of a familial MPN pedigree...

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Detalles Bibliográficos
Autores principales: Braunstein, Evan M., Chen, Hang, Juarez, Felicia, Yang, Fanghan, Tao, Lindsay, Makhlin, Igor, Williams, Donna M., Chaturvedi, Shruti, Pallavajjala, Aparna, Karantanos, Theodoros, Martin, Renan, Wohler, Elizabeth, Sobreira, Nara, Gocke, Christopher D., Moliterno, Alison R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268839/
https://www.ncbi.nlm.nih.gov/pubmed/34209587
http://dx.doi.org/10.3390/cancers13133246

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