Chrysomycin A Attenuates Neuroinflammation by Down-Regulating NLRP3/Cleaved Caspase-1 Signaling Pathway in LPS-Stimulated Mice and BV2 Cells

Chrysomycin A (Chr-A), an antibiotic chrysomycin, was discovered in 1955 and is used to treat cancer and tuberculosis. In the present study, the anti-neuroinflammatory effects and possible mechanism of Chr-A in BALB/c mice and in BV2 microglia cells stimulated by lipopolysaccharide (LPS) were invest...

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Detalles Bibliográficos
Autores principales: Liu, Man, Zhang, Shan-Shan, Liu, Dong-Ni, Yang, Ying-Lin, Wang, Yue-Hua, Du, Guan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268846/
https://www.ncbi.nlm.nih.gov/pubmed/34202695
http://dx.doi.org/10.3390/ijms22136799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268846/
https://www.ncbi.nlm.nih.gov/pubmed/34202695
http://dx.doi.org/10.3390/ijms22136799

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