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Effect of Lipopolysaccharide-Induced Inflammatory Challenge on β-Glucuronidase Activity and the Concentration of Quercetin and Its Metabolites in the Choroid Plexus, Blood Plasma and Cerebrospinal Fluid
Quercetin-3-glucuronide (Q3GA), the main phase II metabolite of quercetin (Q) in human plasma, is considered to be a more stable form of Q for transport with the bloodstream to tissues, where it can be potentially deconjugated by β-glucuronidase (β-Gluc) to Q aglycone, which easily enters the brain....
Autores principales: | Domżalska, Małgorzata, Wiczkowski, Wiesław, Szczepkowska, Aleksandra, Chojnowska, Sylwia, Misztal, Tomasz, Walter, Fruzsina R., Deli, Maria A., Ishikawa, Hiroshi, Schroten, Horst, Schwerk, Christian, Skipor, Janina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268849/ https://www.ncbi.nlm.nih.gov/pubmed/34281178 http://dx.doi.org/10.3390/ijms22137122 |
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