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Comprehensive Profiling of Hypoxia-Related miRNAs Identifies miR-23a-3p Overexpression as a Marker of Platinum Resistance and Poor Prognosis in High-Grade Serous Ovarian Cancer

SIMPLE SUMMARY: In the present paper, we identified miR-23a-3p, a hypoxia regulated-microRNA (miRNA), as a potential biomarker of chemoresistance and poor outcome in two independent cohorts of high-grade serous ovarian carcinoma (HGSOC) patients. Then, we predicted the involvement of miR-23a-3p in t...

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Detalles Bibliográficos
Autores principales: Todeschini, Paola, Salviato, Elisa, Romani, Chiara, Raimondi, Vittoria, Ciccarese, Francesco, Ferrari, Federico, Tognon, Germana, Marchini, Sergio, D’Incalci, Maurizio, Zanotti, Laura, Ravaggi, Antonella, Odicino, Franco, Sartori, Enrico, D’Agostino, Donna M., Samaja, Michele, Romualdi, Chiara, Bignotti, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268862/
https://www.ncbi.nlm.nih.gov/pubmed/34283087
http://dx.doi.org/10.3390/cancers13133358