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ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, the que...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268868/ https://www.ncbi.nlm.nih.gov/pubmed/34209801 http://dx.doi.org/10.3390/jcm10132902 |
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author | Donders, Gilbert G. G. Grinceviciene, Svitrigaile Haldre, Kai Lonnee-Hoffmann, Risa Donders, Francesca Tsiakalos, Aristotelis Adriaanse, Albert Martinez de Oliveira, José Ault, Kevin Mendling, Werner |
author_facet | Donders, Gilbert G. G. Grinceviciene, Svitrigaile Haldre, Kai Lonnee-Hoffmann, Risa Donders, Francesca Tsiakalos, Aristotelis Adriaanse, Albert Martinez de Oliveira, José Ault, Kevin Mendling, Werner |
author_sort | Donders, Gilbert G. G. |
collection | PubMed |
description | Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, the question arises whether pregnant women should be vaccinated, and if so, whether they should receive priority. Methods. Available scientific data and available guidelines about vaccination against SARS-CoV-2 were collected by the Guideline Committee of the International Society of Infectious Diseases in Obstetrics and Gynecology (ISIDOG) and were analyzed, discussed and summarized as guidelines for healthcare workers caring for pregnant women. Concluding statements were graded according to the Oxford evidence-based medicine grading system. Results. There is evidence to consider pregnancy as a risk factor for serious complications of COVID-19 infection, even in the absence of additional risk factors, such as hypertension, diabetes and obesity which increase these risks even more in pregnancy. Currently available data slightly favor mRNA-based vaccines above vector-based vaccines during pregnancy and breastfeeding, until more safety data become available. Conclusion. ISIDOG advises policy makers and societies to prioritize pregnant women to receive vaccination against SARS-CoV-2 and favor the mRNA vaccines until further safety information becomes available. |
format | Online Article Text |
id | pubmed-8268868 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82688682021-07-10 ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy Donders, Gilbert G. G. Grinceviciene, Svitrigaile Haldre, Kai Lonnee-Hoffmann, Risa Donders, Francesca Tsiakalos, Aristotelis Adriaanse, Albert Martinez de Oliveira, José Ault, Kevin Mendling, Werner J Clin Med Review Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, the question arises whether pregnant women should be vaccinated, and if so, whether they should receive priority. Methods. Available scientific data and available guidelines about vaccination against SARS-CoV-2 were collected by the Guideline Committee of the International Society of Infectious Diseases in Obstetrics and Gynecology (ISIDOG) and were analyzed, discussed and summarized as guidelines for healthcare workers caring for pregnant women. Concluding statements were graded according to the Oxford evidence-based medicine grading system. Results. There is evidence to consider pregnancy as a risk factor for serious complications of COVID-19 infection, even in the absence of additional risk factors, such as hypertension, diabetes and obesity which increase these risks even more in pregnancy. Currently available data slightly favor mRNA-based vaccines above vector-based vaccines during pregnancy and breastfeeding, until more safety data become available. Conclusion. ISIDOG advises policy makers and societies to prioritize pregnant women to receive vaccination against SARS-CoV-2 and favor the mRNA vaccines until further safety information becomes available. MDPI 2021-06-29 /pmc/articles/PMC8268868/ /pubmed/34209801 http://dx.doi.org/10.3390/jcm10132902 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Donders, Gilbert G. G. Grinceviciene, Svitrigaile Haldre, Kai Lonnee-Hoffmann, Risa Donders, Francesca Tsiakalos, Aristotelis Adriaanse, Albert Martinez de Oliveira, José Ault, Kevin Mendling, Werner ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy |
title | ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy |
title_full | ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy |
title_fullStr | ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy |
title_full_unstemmed | ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy |
title_short | ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy |
title_sort | isidog consensus guidelines on covid-19 vaccination for women before, during and after pregnancy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268868/ https://www.ncbi.nlm.nih.gov/pubmed/34209801 http://dx.doi.org/10.3390/jcm10132902 |
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