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ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy

Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, the que...

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Autores principales: Donders, Gilbert G. G., Grinceviciene, Svitrigaile, Haldre, Kai, Lonnee-Hoffmann, Risa, Donders, Francesca, Tsiakalos, Aristotelis, Adriaanse, Albert, Martinez de Oliveira, José, Ault, Kevin, Mendling, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268868/
https://www.ncbi.nlm.nih.gov/pubmed/34209801
http://dx.doi.org/10.3390/jcm10132902
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author Donders, Gilbert G. G.
Grinceviciene, Svitrigaile
Haldre, Kai
Lonnee-Hoffmann, Risa
Donders, Francesca
Tsiakalos, Aristotelis
Adriaanse, Albert
Martinez de Oliveira, José
Ault, Kevin
Mendling, Werner
author_facet Donders, Gilbert G. G.
Grinceviciene, Svitrigaile
Haldre, Kai
Lonnee-Hoffmann, Risa
Donders, Francesca
Tsiakalos, Aristotelis
Adriaanse, Albert
Martinez de Oliveira, José
Ault, Kevin
Mendling, Werner
author_sort Donders, Gilbert G. G.
collection PubMed
description Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, the question arises whether pregnant women should be vaccinated, and if so, whether they should receive priority. Methods. Available scientific data and available guidelines about vaccination against SARS-CoV-2 were collected by the Guideline Committee of the International Society of Infectious Diseases in Obstetrics and Gynecology (ISIDOG) and were analyzed, discussed and summarized as guidelines for healthcare workers caring for pregnant women. Concluding statements were graded according to the Oxford evidence-based medicine grading system. Results. There is evidence to consider pregnancy as a risk factor for serious complications of COVID-19 infection, even in the absence of additional risk factors, such as hypertension, diabetes and obesity which increase these risks even more in pregnancy. Currently available data slightly favor mRNA-based vaccines above vector-based vaccines during pregnancy and breastfeeding, until more safety data become available. Conclusion. ISIDOG advises policy makers and societies to prioritize pregnant women to receive vaccination against SARS-CoV-2 and favor the mRNA vaccines until further safety information becomes available.
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spelling pubmed-82688682021-07-10 ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy Donders, Gilbert G. G. Grinceviciene, Svitrigaile Haldre, Kai Lonnee-Hoffmann, Risa Donders, Francesca Tsiakalos, Aristotelis Adriaanse, Albert Martinez de Oliveira, José Ault, Kevin Mendling, Werner J Clin Med Review Introduction. Sars-CoV-2 infection poses particular problems in pregnancy, as the infection more frequently causes severe complications than in unaffected pregnant women or nonpregnant women with SARS-CoV-2 infection. Now that vaccination is available and rapidly being implemented worldwide, the question arises whether pregnant women should be vaccinated, and if so, whether they should receive priority. Methods. Available scientific data and available guidelines about vaccination against SARS-CoV-2 were collected by the Guideline Committee of the International Society of Infectious Diseases in Obstetrics and Gynecology (ISIDOG) and were analyzed, discussed and summarized as guidelines for healthcare workers caring for pregnant women. Concluding statements were graded according to the Oxford evidence-based medicine grading system. Results. There is evidence to consider pregnancy as a risk factor for serious complications of COVID-19 infection, even in the absence of additional risk factors, such as hypertension, diabetes and obesity which increase these risks even more in pregnancy. Currently available data slightly favor mRNA-based vaccines above vector-based vaccines during pregnancy and breastfeeding, until more safety data become available. Conclusion. ISIDOG advises policy makers and societies to prioritize pregnant women to receive vaccination against SARS-CoV-2 and favor the mRNA vaccines until further safety information becomes available. MDPI 2021-06-29 /pmc/articles/PMC8268868/ /pubmed/34209801 http://dx.doi.org/10.3390/jcm10132902 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Donders, Gilbert G. G.
Grinceviciene, Svitrigaile
Haldre, Kai
Lonnee-Hoffmann, Risa
Donders, Francesca
Tsiakalos, Aristotelis
Adriaanse, Albert
Martinez de Oliveira, José
Ault, Kevin
Mendling, Werner
ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
title ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
title_full ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
title_fullStr ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
title_full_unstemmed ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
title_short ISIDOG Consensus Guidelines on COVID-19 Vaccination for Women before, during and after Pregnancy
title_sort isidog consensus guidelines on covid-19 vaccination for women before, during and after pregnancy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268868/
https://www.ncbi.nlm.nih.gov/pubmed/34209801
http://dx.doi.org/10.3390/jcm10132902
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