Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties

PEGylation of antimicrobial peptides as a shielding tool that increases stability toward proteolytic degradation typically leads to concomitant loss of activity, whereas incorporation of ultrashort PEG-like amino acids (sPEGs) remains essentially unexplored. Here, modification of a peptide/β-peptoid...

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Detalles Bibliográficos
Autores principales: Frederiksen, Nicki, Louka, Stavroula, Mudaliar, Chirag, Domraceva, Ilona, Kreicberga, Agrita, Pugovics, Osvalds, Żabicka, Dorota, Tomczak, Magdalena, Wygoda, Weronika, Björkling, Fredrik, Franzyk, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268887/
https://www.ncbi.nlm.nih.gov/pubmed/34208826
http://dx.doi.org/10.3390/ijms22137041

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