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Restriction of Manganese Intake Prevents the Onset of Brain Manganese Overload in Zip14(−/−) Mice
As a newly identified manganese transport protein, ZIP14 is highly expressed in the small intestine and liver, which are the two principal organs involved in regulating systemic manganese homeostasis. Loss of ZIP14 function leads to manganese overload in both humans and mice. Excess manganese in the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268934/ https://www.ncbi.nlm.nih.gov/pubmed/34202493 http://dx.doi.org/10.3390/ijms22136773 |