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Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma

SIMPLE SUMMARY: Aqueous humor (AH) liquid biopsy is an enriched source of cell-free circulating tumor-derived DNA for retinoblastoma (RB). The use of this AH liquid biopsy allows for genomic analysis of eyes in the absence of tumor tissue. Development of this platform was critical because direct tum...

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Detalles Bibliográficos
Autores principales: Kim, Mary E., Polski, Ashley, Xu, Liya, Prabakar, Rishvanth K., Peng, Chen-Ching, Reid, Mark W., Shah, Rachana, Kuhn, Peter, Cobrinik, David, Hicks, James, Berry, Jesse L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268955/
https://www.ncbi.nlm.nih.gov/pubmed/34283049
http://dx.doi.org/10.3390/cancers13133340