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Low-Dose Acrolein, an Endogenous and Exogenous Toxic Molecule, Inhibits Glucose Transport via an Inhibition of Akt-Regulated GLUT4 Signaling in Skeletal Muscle Cells

Urinary acrolein adduct levels have been reported to be increased in both habitual smokers and type-2 diabetic patients. The impairment of glucose transport in skeletal muscles is a major factor responsible for glucose uptake reduction in type-2 diabetic patients. The effect of acrolein on glucose m...

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Detalles Bibliográficos
Autores principales: Wang, Ching-Chia, Chen, Huang-Jen, Chan, Ding-Cheng, Chiu, Chen-Yuan, Liu, Shing-Hwa, Lan, Kuo-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268984/
https://www.ncbi.nlm.nih.gov/pubmed/34281282
http://dx.doi.org/10.3390/ijms22137228