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Low-Dose Acrolein, an Endogenous and Exogenous Toxic Molecule, Inhibits Glucose Transport via an Inhibition of Akt-Regulated GLUT4 Signaling in Skeletal Muscle Cells
Urinary acrolein adduct levels have been reported to be increased in both habitual smokers and type-2 diabetic patients. The impairment of glucose transport in skeletal muscles is a major factor responsible for glucose uptake reduction in type-2 diabetic patients. The effect of acrolein on glucose m...
Autores principales: | Wang, Ching-Chia, Chen, Huang-Jen, Chan, Ding-Cheng, Chiu, Chen-Yuan, Liu, Shing-Hwa, Lan, Kuo-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268984/ https://www.ncbi.nlm.nih.gov/pubmed/34281282 http://dx.doi.org/10.3390/ijms22137228 |
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