Cargando…

Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells

Pancracine, a montanine-type Amaryllidaceae alkaloid (AA), is one of the most potent compounds among natural isoquinolines. In previous studies, pancracine exhibited cytotoxic activity against diverse human cancer cell lines in vitro. However, further insight into the molecular mechanisms that under...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koutová, Darja, Havelek, Radim, Peterová, Eva, Muthná, Darina, Královec, Karel, Breiterová, Kateřina, Cahlíková, Lucie, Řezáčová, Martina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269071/ https://www.ncbi.nlm.nih.gov/pubmed/34209868 http://dx.doi.org/10.3390/ijms22137014

Ejemplares similares

Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family
por: Koutová, Darja, et al.
Publicado: (2020)

Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities
por: Ritomská, Aneta, et al.
Publicado: (2023)

Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells
por: Koutova, Darja, et al.
Publicado: (2020)

Amaryllidaceae Alkaloids of Different Structural Types from Narcissus L. cv. Professor Einstein and Their Cytotoxic Activity
por: Breiterová, Kateřina, et al.
Publicado: (2020)

Chemistry and Biological Activity of Alkaloids from the Genus Lycoris (Amaryllidaceae)
por: Cahlíková, Lucie, et al.
Publicado: (2020)

Amaryllidaceae alkaloids: identification and partial characterization of montanine production in Rhodophiala bifida plant
por: Reis, Andressa, et al.
Publicado: (2019)

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents
por: Maafi, Negar, et al.
Publicado: (2021)

Author Correction: Amaryllidaceae alkaloids: identification and partial characterization of montanine production in Rhodophiala bifida plant
por: Reis, Andressa, et al.
Publicado: (2019)

Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells
por: Habartova, Klara, et al.
Publicado: (2018)

The Genus Nerine Herb. (Amaryllidaceae): Ethnobotany, Phytochemistry, and Biological Activity
por: Cahlíková, Lucie, et al.
Publicado: (2019)

Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores
por: Bui, Duong Thuy, et al.
Publicado: (2022)

Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors
por: Hulcová, Daniela, et al.
Publicado: (2018)

The effect of sodium butyrate and cisplatin on expression of EMT markers
por: Mrkvicova, Alena, et al.
Publicado: (2019)

Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s Disease
por: Kohelová, Eliška, et al.
Publicado: (2019)

Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro
por: Breiterová, Kateřina Hradiská, et al.
Publicado: (2023)

Disruption of Cell Adhesion and Cytoskeletal Networks by Thiol-Functionalized Silica-Coated Iron Oxide Nanoparticles
por: Královec, Karel, et al.
Publicado: (2020)

The Effect of Chronic Exposure of Graphene Nanoplates on the Viability and Motility of A549 Cells
por: Šestáková, Blanka, et al.
Publicado: (2022)

Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity
por: Šafratová, Marcela, et al.
Publicado: (2022)

Substituted Piperazines as Novel Potential Radioprotective Agents
por: Filipova, Alzbeta, et al.
Publicado: (2020)

D-carvone induced ROS mediated apoptotic cell death in human leukemic cell lines (Molt-4)
por: Iyappan, Petchi, et al.
Publicado: (2021)

Antiparasitic Activity of Hippeastrum Species and Synergistic Interaction between Montanine and Benznidazole against Trypanosoma cruzi
por: Piñeiro, Mauricio, et al.
Publicado: (2023)

Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer’s Disease
por: Cahlíková, Lucie, et al.
Publicado: (2021)

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction
por: SUCHA, LENKA, et al.
Publicado: (2013)

Synthesis, Characterization, and Antiproliferative Effect of CuO-TiO(2)-Chitosan-Amygdalin Nanocomposites in Human Leukemic MOLT4 Cells
por: Elderdery, Abozer Y., et al.
Publicado: (2022)

Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids
por: Maříková, Jana, et al.
Publicado: (2021)

Synthesis, Characterization, and Antimicrobial and Antiproliferative Effects of CuO-TiO(2)-Chitosan-Escin Nanocomposites on Human Leukemic MOLT4 Cells
por: Elderdery, Abozer Y., et al.
Publicado: (2022)

Radiosensitization of Human Leukemic HL-60 Cells by ATR Kinase Inhibitor (VE-821): Phosphoproteomic Analysis
por: Šalovská, Barbora, et al.
Publicado: (2014)

Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase
por: Al Mamun, Abdullah, et al.
Publicado: (2020)

Two new species of endemic Ecuadorean Amaryllidaceae (Asparagales, Amaryllidaceae, Amarylloideae, Eucharideae)
por: Meerow, Alan W., et al.
Publicado: (2015)

Primary molt in Gruiforms and simpler molt summary tables
por: Rohwer, Sievert, et al.
Publicado: (2018)

The role of mitochondrial proteases in leukemic cells and leukemic stem cells
por: Mirali, Sara, et al.
Publicado: (2020)

IMMUNOLOGICAL FUNCTIONS OF HUMAN T-LYMPHOID CELL LINE (MOLT) : I. RELEASE OF IMMUNOSUPPRESSIVE FACTORS FROM THE MIXTURE OF MOLT-4 CELLS AND SHEEP RED BLOOD CELLS
por: Takada, Akikazu, et al.
Publicado: (1974)

Recent Progress in Amaryllidaceae Biotechnology
por: Georgiev, Vasil, et al.
Publicado: (2020)

Evaluation of different non-fasting molting methods on laying performance and egg quality during molting and post molting periods
por: Ga, Gun Whi, et al.
Publicado: (2022)

Synthesis of Zinc Oxide (ZnO)-Titanium Dioxide (TiO(2))-Chitosan-Farnesol Nanocomposites and Assessment of Their Anticancer Potential in Human Leukemic MOLT-4 Cell Line
por: Elderdery, Abozer Y., et al.
Publicado: (2022)

Exoskeleton anchoring to tendon cells and muscles in molting isopod crustaceans
por: Žnidaršič, Nada, et al.
Publicado: (2012)

Tissue mRNA for S100A4, S100A6, S100A8, S100A9, S100A11 and S100P Proteins in Colorectal Neoplasia: A Pilot Study
por: Peterova, Eva, et al.
Publicado: (2021)

Efficiency of Herkogamy in Narcissus bulbocodium (Amaryllidaceae)
por: Navarro, Luis, et al.
Publicado: (2021)

Fluorouracil Selectively Enriches Stem-like Leukemic Cells in a Leukemic Cell Line
por: Zhang, Ling, et al.
Publicado: (2010)

Leukemic Stem Cells: From Leukemic Niche Biology to Treatment Opportunities
por: Marchand, Tony, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hklod9ghq6k2kh3f6nrlo7nfua