The Effect of DREADD Activation of Leptin Receptor Positive Neurons in the Nucleus of the Solitary Tract on Sleep Disordered Breathing

Obstructive sleep apnea (OSA) is recurrent obstruction of the upper airway due to the loss of upper airway muscle tone during sleep. OSA is highly prevalent, especially in obesity. There is no pharmacotherapy for OSA. Previous studies have demonstrated the role of leptin, an adipose-tissue-produced...

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Detalles Bibliográficos
Autores principales: Amorim, Mateus R., Dergacheva, Olga, Fleury-Curado, Thomaz, Pho, Huy, Freire, Carla, Mendelowitz, David, Branco, Luiz G. S., Polotsky, Vsevolod Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269100/
https://www.ncbi.nlm.nih.gov/pubmed/34201760
http://dx.doi.org/10.3390/ijms22136742

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