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Elucidating the Mechanism of Action of the Attributed Immunomodulatory Role of Eltrombopag in Primary Immune Thrombocytopenia: An In Silico Approach
Eltrombopag is a thrombopoietin receptor (MPL) agonist approved for the treatment of primary immune thrombocytopenia (ITP). Recent evidence shows that some patients may sustain platelet counts following eltrombopag discontinuation. The systemic immunomodulatory response that resolves ITP in some pat...
Autores principales: | Lozano, Maria L., Segú-Vergés, Cristina, Coma, Mireia, Álvarez-Roman, María T., González-Porras, José R., Gutiérrez, Laura, Valcárcel, David, Butta, Nora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269123/ https://www.ncbi.nlm.nih.gov/pubmed/34199099 http://dx.doi.org/10.3390/ijms22136907 |
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