Cargando…
Molecular and Neural Mechanism of Dysphagia Due to Cancer
Cancer is one of the most common causes of death worldwide. Along with the advances in diagnostic technology achieved through industry–academia partnerships, the survival rate of cancer patients has improved dramatically through treatments that include surgery, radiation therapy, and pharmacotherapy...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269194/ https://www.ncbi.nlm.nih.gov/pubmed/34210012 http://dx.doi.org/10.3390/ijms22137033 |
_version_ | 1783720523122868224 |
---|---|
author | Okuni, Ikuko Otsubo, Yuta Ebihara, Satoru |
author_facet | Okuni, Ikuko Otsubo, Yuta Ebihara, Satoru |
author_sort | Okuni, Ikuko |
collection | PubMed |
description | Cancer is one of the most common causes of death worldwide. Along with the advances in diagnostic technology achieved through industry–academia partnerships, the survival rate of cancer patients has improved dramatically through treatments that include surgery, radiation therapy, and pharmacotherapy. This has increased the population of cancer “survivors” and made cancer survivorship an important part of life for patients. The senses of taste and smell during swallowing and cachexia play important roles in dysphagia associated with nutritional disorders in cancer patients. Cancerous lesions in the brain can cause dysphagia. Taste and smell disorders that contribute to swallowing can worsen or develop because of pharmacotherapy or radiation therapy; metabolic or central nervous system damage due to cachexia, sarcopenia, or inflammation can also cause dysphagia. As the causes of eating disorders in cancer patients are complex and involve multiple factors, cancer patients require a multifaceted and long-term approach by the medical care team. |
format | Online Article Text |
id | pubmed-8269194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82691942021-07-10 Molecular and Neural Mechanism of Dysphagia Due to Cancer Okuni, Ikuko Otsubo, Yuta Ebihara, Satoru Int J Mol Sci Review Cancer is one of the most common causes of death worldwide. Along with the advances in diagnostic technology achieved through industry–academia partnerships, the survival rate of cancer patients has improved dramatically through treatments that include surgery, radiation therapy, and pharmacotherapy. This has increased the population of cancer “survivors” and made cancer survivorship an important part of life for patients. The senses of taste and smell during swallowing and cachexia play important roles in dysphagia associated with nutritional disorders in cancer patients. Cancerous lesions in the brain can cause dysphagia. Taste and smell disorders that contribute to swallowing can worsen or develop because of pharmacotherapy or radiation therapy; metabolic or central nervous system damage due to cachexia, sarcopenia, or inflammation can also cause dysphagia. As the causes of eating disorders in cancer patients are complex and involve multiple factors, cancer patients require a multifaceted and long-term approach by the medical care team. MDPI 2021-06-29 /pmc/articles/PMC8269194/ /pubmed/34210012 http://dx.doi.org/10.3390/ijms22137033 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Okuni, Ikuko Otsubo, Yuta Ebihara, Satoru Molecular and Neural Mechanism of Dysphagia Due to Cancer |
title | Molecular and Neural Mechanism of Dysphagia Due to Cancer |
title_full | Molecular and Neural Mechanism of Dysphagia Due to Cancer |
title_fullStr | Molecular and Neural Mechanism of Dysphagia Due to Cancer |
title_full_unstemmed | Molecular and Neural Mechanism of Dysphagia Due to Cancer |
title_short | Molecular and Neural Mechanism of Dysphagia Due to Cancer |
title_sort | molecular and neural mechanism of dysphagia due to cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269194/ https://www.ncbi.nlm.nih.gov/pubmed/34210012 http://dx.doi.org/10.3390/ijms22137033 |
work_keys_str_mv | AT okuniikuko molecularandneuralmechanismofdysphagiaduetocancer AT otsuboyuta molecularandneuralmechanismofdysphagiaduetocancer AT ebiharasatoru molecularandneuralmechanismofdysphagiaduetocancer |