Post Zygotic, Somatic, Deletion in KERATIN 1 V1 Domain Generates Structural Alteration of the K1/K10 Dimer, Producing a Monolateral Palmar Epidermolytic Nevus

Palmoplantar keratodermas (PPKs) are characterized by thickness of stratum corneum and epidermal hyperkeratosis localized in palms and soles. PPKs can be epidermolytic (EPPK) or non epidermolytic (NEPPK). Specific mutations of keratin 16 (K16) and keratin 1 (K1) have been associated to EPPK, and NEP...

Descripción completa

Detalles Bibliográficos
Autores principales: Caporali, Sabrina, Didona, Biagio, Paradisi, Mauro, Mauriello, Alessandro, Campione, Elena, Falconi, Mattia, Iacovelli, Federico, Minieri, Marilena, Pieri, Massimo, Bernardini, Sergio, Terrinoni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269197/
https://www.ncbi.nlm.nih.gov/pubmed/34199056
http://dx.doi.org/10.3390/ijms22136901

Ejemplares similares

Ejemplares similares