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Genome-Scale Metabolic Model of Caldicellulosiruptor bescii Reveals Optimal Metabolic Engineering Strategies for Bio-based Chemical Production

Metabolic modeling was used to examine potential bottlenecks that could be encountered for metabolic engineering of the cellulolytic extreme thermophile Caldicellulosiruptor bescii to produce bio-based chemicals from plant biomass. The model utilizes subsystems-based genome annotation, targeted reco...

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Detalles Bibliográficos
Autores principales: Zhang, Ke, Zhao, Weishu, Rodionov, Dmitry A., Rubinstein, Gabriel M., Nguyen, Diep N., Tanwee, Tania N. N., Crosby, James, Bing, Ryan G., Kelly, Robert M., Adams, Michael W. W., Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269263/
https://www.ncbi.nlm.nih.gov/pubmed/34060912
http://dx.doi.org/10.1128/mSystems.01351-20