PD-1 and beyond to Activate T Cells in Cutaneous Squamous Cell Cancers: The Case for 4-1BB and VISTA Antibodies in Combination Therapy

SIMPLE SUMMARY: The use of checkpoint antibodies has revolutionized the treatment of cancer. Tumor-infiltrating T cells, key mediators of anti-tumor immune responses, are often actively silenced by the tumor microenvironment. Checkpoint antibodies block inhibitory signals or enhance positive signali...

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Detalles Bibliográficos
Autores principales: Wright, Quentin, Gonzalez Cruz, Jazmina L., Wells, James W., Leggatt, Graham R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269268/
https://www.ncbi.nlm.nih.gov/pubmed/34282763
http://dx.doi.org/10.3390/cancers13133310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269268/
https://www.ncbi.nlm.nih.gov/pubmed/34282763
http://dx.doi.org/10.3390/cancers13133310

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