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Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways

Spermatogenic dysfunction caused by cyclophosphamide (CP) chemotherapy has seriously influenced the life quality of patients. Unfortunately, treatments for CP-induced testicular spermatogenic dysfunction are limited, and the molecular mechanisms are not fully understood. For the first time, here, we...

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Detalles Bibliográficos
Autores principales: Guo, Xiao-Bin, Zhai, Jia-Wen, Xia, Hui, Yang, Jian-Kun, Zhou, Jun-Hao, Guo, Wen-Bin, Yang, Cheng, Xia, Ming, Xue, Kang-Yi, Liu, Cun-Dong, Zhou, Qi-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269825/
https://www.ncbi.nlm.nih.gov/pubmed/33565424
http://dx.doi.org/10.4103/aja.aja_98_20