Quadrivalent influenza nanoparticle vaccines induce broad protection

Influenza vaccines that confer broad and durable protection against diverse virus strains would have a major impact on global health(1). Here we show that computationally designed, two-component nanoparticle immunogens(2) induce potently neutralizing and broadly protective antibody responses against...

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Detalles Bibliográficos
Autores principales: Boyoglu-Barnum, Seyhan, Ellis, Daniel, Gillespie, Rebecca A., Hutchinson, Geoffrey B., Park, Young-Jun, Moin, Syed M., Acton, Oliver J., Ravichandran, Rashmi, Murphy, Mike, Pettie, Deleah, Matheson, Nick, Carter, Lauren, Creanga, Adrian, Watson, Michael J., Kephart, Sally, Ataca, Sila, Vaile, John R., Ueda, George, Crank, Michelle C., Stewart, Lance, Lee, Kelly K., Guttman, Miklos, Baker, David, Mascola, John R., Veesler, David, Graham, Barney S., King, Neil P., Kanekiyo, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269962/
https://www.ncbi.nlm.nih.gov/pubmed/33762730
http://dx.doi.org/10.1038/s41586-021-03365-x

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