Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF

Determination of the metabolism pathway of xenobiotics undergoing the hepatic pass is a crucial aspect in drug development since the presence of toxic biotransformation products may result in significant side effects during the therapy. In this study, the complete hepatic metabolism pathway of dapox...

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Detalles Bibliográficos
Autores principales: Skibiński, Robert, Trawiński, Jakub, Gawlik, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270242/
https://www.ncbi.nlm.nih.gov/pubmed/34206424
http://dx.doi.org/10.3390/molecules26133794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270242/
https://www.ncbi.nlm.nih.gov/pubmed/34206424
http://dx.doi.org/10.3390/molecules26133794

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