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Biotransformation of Timosaponin BII into Seven Characteristic Metabolites by the Gut Microbiota
Timosaponin BII is one of the most abundant Anemarrhena saponins and is in a phase II clinical trial for the treatment of dementia. However, the pharmacological activity of timosaponin BII does not match its low bioavailability. In this study, we aimed to determine the effects of gut microbiota on t...
Autores principales: | Dong, Guo-Ming, Yu, Hang, Pan, Li-Bin, Ma, Shu-Rong, Xu, Hui, Zhang, Zheng-Wei, Han, Pei, Fu, Jie, Yang, Xin-Yu, Keranmu, Adili, Niu, Hai-Tao, Jiang, Jian-Dong, Wang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270264/ https://www.ncbi.nlm.nih.gov/pubmed/34202717 http://dx.doi.org/10.3390/molecules26133861 |
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