Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

HIV associated immune activation (IA) is associated with increased morbidity in people living with HIV (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed at reducing the HIV reservoir. The underlying mechanisms of IA have not been definitively elucidated, however, persisten...

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Detalles Bibliográficos
Autores principales: Lee, Michelle Y.-H., Upadhyay, Amit A., Walum, Hasse, Chan, Chi N., Dawoud, Reem A., Grech, Christine, Harper, Justin L., Karunakaran, Kirti A., Nelson, Sydney A., Mahar, Ernestine A., Goss, Kyndal L., Carnathan, Diane G., Cervasi, Barbara, Gill, Kiran, Tharp, Gregory K., Wonderlich, Elizabeth R., Velu, Vijayakumar, Barratt-Boyes, Simon M., Paiardini, Mirko, Silvestri, Guido, Estes, Jacob D., Bosinger, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270445/
https://www.ncbi.nlm.nih.gov/pubmed/34181694
http://dx.doi.org/10.1371/journal.ppat.1009674

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