Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway

The response of endothelial cells to mechanical forces is a critical determinant of vascular health. Vascular pathologies, such as atherosclerosis, characterized by abnormal mechanical forces are frequently accompanied by endothelial-to-mesenchymal transition (EndMT). However, how forces affect the...

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Detalles Bibliográficos
Autores principales: Mehta, Vedanta, Pang, Kar-Lai, Givens, Christopher S., Chen, Zhongming, Huang, Jianhua, Sweet, Daniel T., Jo, Hanjoong, Reader, John S., Tzima, Ellie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270486/
https://www.ncbi.nlm.nih.gov/pubmed/34244146
http://dx.doi.org/10.1126/sciadv.abg5060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270486/
https://www.ncbi.nlm.nih.gov/pubmed/34244146
http://dx.doi.org/10.1126/sciadv.abg5060

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