A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors

Neuroendocrine tumors (NETs) are unusual neoplasms with a diverse spectrum of clinical presentations. There is a lack of literature on cases of 2 primary histologically distinct NETs. We report a case of a 40-year-old man who presented with chronic diarrhea. A colonoscopy was performed which discove...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Ashley A., Suhail, Fathima K., Mirchia, Kanish, Rawlins, Sekou R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270576/
https://www.ncbi.nlm.nih.gov/pubmed/34258305
http://dx.doi.org/10.14309/crj.0000000000000625
_version_ 1783720823984488448
author Thompson, Ashley A.
Suhail, Fathima K.
Mirchia, Kanish
Rawlins, Sekou R.
author_facet Thompson, Ashley A.
Suhail, Fathima K.
Mirchia, Kanish
Rawlins, Sekou R.
author_sort Thompson, Ashley A.
collection PubMed
description Neuroendocrine tumors (NETs) are unusual neoplasms with a diverse spectrum of clinical presentations. There is a lack of literature on cases of 2 primary histologically distinct NETs. We report a case of a 40-year-old man who presented with chronic diarrhea. A colonoscopy was performed which discovered a rectal polyp, with pathology showing a well-differentiated NET. A subsequent somatostatin scan revealed a pancreatic tail mass. Biopsy showed a histologically distinct well-differentiated vasoactive intestinal peptide-producing NET. Given that pancreatic and rectal NETs come from different embryonic origins, the diagnosis of 2 primary NETs presents a unique case.
format Online
Article
Text
id pubmed-8270576
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Wolters Kluwer
record_format MEDLINE/PubMed
spelling pubmed-82705762021-07-12 A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors Thompson, Ashley A. Suhail, Fathima K. Mirchia, Kanish Rawlins, Sekou R. ACG Case Rep J Case Report Neuroendocrine tumors (NETs) are unusual neoplasms with a diverse spectrum of clinical presentations. There is a lack of literature on cases of 2 primary histologically distinct NETs. We report a case of a 40-year-old man who presented with chronic diarrhea. A colonoscopy was performed which discovered a rectal polyp, with pathology showing a well-differentiated NET. A subsequent somatostatin scan revealed a pancreatic tail mass. Biopsy showed a histologically distinct well-differentiated vasoactive intestinal peptide-producing NET. Given that pancreatic and rectal NETs come from different embryonic origins, the diagnosis of 2 primary NETs presents a unique case. Wolters Kluwer 2021-07-08 /pmc/articles/PMC8270576/ /pubmed/34258305 http://dx.doi.org/10.14309/crj.0000000000000625 Text en © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Thompson, Ashley A.
Suhail, Fathima K.
Mirchia, Kanish
Rawlins, Sekou R.
A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors
title A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors
title_full A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors
title_fullStr A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors
title_full_unstemmed A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors
title_short A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors
title_sort case of profound secretory diarrhea revealing 2 primary neuroendocrine tumors
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270576/
https://www.ncbi.nlm.nih.gov/pubmed/34258305
http://dx.doi.org/10.14309/crj.0000000000000625
work_keys_str_mv AT thompsonashleya acaseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT suhailfathimak acaseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT mirchiakanish acaseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT rawlinssekour acaseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT thompsonashleya caseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT suhailfathimak caseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT mirchiakanish caseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors
AT rawlinssekour caseofprofoundsecretorydiarrhearevealing2primaryneuroendocrinetumors

Ejemplares similares