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Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma
Angiosarcomas are vascular malignancies with a tendency to spread extensively both locally and systemically. We report a case of cutaneous angiosarcoma of the face in a 53-year-old man that was originally misdiagnosed as an abscess. Initially small, the lesion enlarged over a four-to-six-month perio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270714/ https://www.ncbi.nlm.nih.gov/pubmed/34306782 http://dx.doi.org/10.1155/2021/8823585 |
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author | Lara-Martinez, Hugo Weinberg, Molly Baratam, Praneeth Horn, Jeffrey Ward, Kristine Styler, Michael |
author_facet | Lara-Martinez, Hugo Weinberg, Molly Baratam, Praneeth Horn, Jeffrey Ward, Kristine Styler, Michael |
author_sort | Lara-Martinez, Hugo |
collection | PubMed |
description | Angiosarcomas are vascular malignancies with a tendency to spread extensively both locally and systemically. We report a case of cutaneous angiosarcoma of the face in a 53-year-old man that was originally misdiagnosed as an abscess. Initially small, the lesion enlarged over a four-to-six-month period and began to bleed. Two shave biopsies were performed that returned a diagnosis of angiosarcoma. The patient underwent radical resection and lymph node dissection, which revealed positive margins and ten of forty-six positive lymph nodes. The patient was treated with paclitaxel and concurrent radiation therapy (RT). Restaging scans showed a new sclerotic lesion of the T10 vertebra, three hepatic lesions, and an adrenal lesion, all concerning for metastasis. Biopsy of one of the hepatic lesions was consistent with metastatic angiosarcoma. In this review, we discuss the presentation of cutaneous angiosarcoma, the importance of early diagnosis, and the treatment options available for metastatic disease that has failed first-line chemotherapy. |
format | Online Article Text |
id | pubmed-8270714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-82707142021-07-22 Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma Lara-Martinez, Hugo Weinberg, Molly Baratam, Praneeth Horn, Jeffrey Ward, Kristine Styler, Michael Case Rep Oncol Med Case Report Angiosarcomas are vascular malignancies with a tendency to spread extensively both locally and systemically. We report a case of cutaneous angiosarcoma of the face in a 53-year-old man that was originally misdiagnosed as an abscess. Initially small, the lesion enlarged over a four-to-six-month period and began to bleed. Two shave biopsies were performed that returned a diagnosis of angiosarcoma. The patient underwent radical resection and lymph node dissection, which revealed positive margins and ten of forty-six positive lymph nodes. The patient was treated with paclitaxel and concurrent radiation therapy (RT). Restaging scans showed a new sclerotic lesion of the T10 vertebra, three hepatic lesions, and an adrenal lesion, all concerning for metastasis. Biopsy of one of the hepatic lesions was consistent with metastatic angiosarcoma. In this review, we discuss the presentation of cutaneous angiosarcoma, the importance of early diagnosis, and the treatment options available for metastatic disease that has failed first-line chemotherapy. Hindawi 2021-07-01 /pmc/articles/PMC8270714/ /pubmed/34306782 http://dx.doi.org/10.1155/2021/8823585 Text en Copyright © 2021 Hugo Lara-Martinez et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lara-Martinez, Hugo Weinberg, Molly Baratam, Praneeth Horn, Jeffrey Ward, Kristine Styler, Michael Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma |
title | Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma |
title_full | Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma |
title_fullStr | Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma |
title_full_unstemmed | Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma |
title_short | Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma |
title_sort | angiosarcoma of the face: a case study and literature review of local and metastatic angiosarcoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270714/ https://www.ncbi.nlm.nih.gov/pubmed/34306782 http://dx.doi.org/10.1155/2021/8823585 |
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