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Exosomes secreted from sonic hedgehog-modified bone mesenchymal stem cells facilitate the repair of rat spinal cord injuries
BACKGROUND: Spinal cord injuries (SCIs) can cause a loss of neurons and associated sensory and motor functionality below the injured site. No approaches to treating SCIs in humans have been developed to date. Exosomes are extracellular vesicles that hold promise as a potential therapeutic modality w...
Autores principales: | Jia, Yijia, Lu, Tingsheng, Chen, Qiling, Pu, Xingwei, Ji, Linsong, Yang, Jianwen, Luo, Chunshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270837/ https://www.ncbi.nlm.nih.gov/pubmed/33821317 http://dx.doi.org/10.1007/s00701-021-04829-9 |
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