Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer’s disease and related tauopathies

Evidence indicates that tau hyper-phosphorylation and subsequent neurofibrillary tangle formation contribute to the extensive neuronal death in Alzheimer’s disease (AD) and related tauopathies. Recent work has identified that increased tau acetylation can promote tau phosphorylation. Tau acetylation...

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Detalles Bibliográficos
Autores principales: Dave, Nikhil, Vural, Austin S., Piras, Ignazio S., Winslow, Wendy, Surendra, Likith, Winstone, Joanna K., Beach, Thomas G., Huentelman, Matthew J., Velazquez, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270842/
https://www.ncbi.nlm.nih.gov/pubmed/33978814
http://dx.doi.org/10.1007/s00401-021-02323-1

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